Allogeneic mesenchymal stem cells transplantation in patients with refractory RA
Read moreHigh Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation for Rheumatoid Arthritis: A Review
Read moreHematopoietic Cell Transplantation for Autoimmune Disease: Updates from Europe and the United States
Read moreEndogenous insulin deficiency is the tie that binds all forms of diabetes. Definitive treatment or cure of type 1 and type 2 diabetes cannot occur without a durable reversal of relative or absolute endogenous insulin deficiency. Current efforts to restore physiological insulin secretion include (1) islet or pancreas transplant; (2) exogenous cell therapies, including differentiation of bone marrow cells and embryonic stem cells (ESCs); and (3) islet regeneration from endogenous pancreatic cells.
Read moreHaematopoietic stem cell transplantation in the treatment of severe autoimmune disease: results from phase I/II studies, prospective randomized trials and future directions
Around 700 patients have received an autologous haematopoietic stem cell transplant (HSCT) as treatment for a severe autoimmune disease (AD)
Read moreThe discovery of human embryonic stem cells (hESCs) raised promises for a universal resource for cell based therapies in regenerat ive medicine. Recentl y, fast-paced progress has been made towards the generation of pluripotent stem cells (PSCs) amenable for clinical applications, culmina ting in reprogramming of adult somatic cells to autologous PSCs that can be indefinitely expandedinvitro.
Read moreAbstract Tendon-bone healing is important for the successful reconstruction of the anterior cruciate ligament by using the hamstring tendon. Mesenchymal stem cells (MSCs) have attracted much interest because of their self-renewing potential and multipotentiality for possible clinical use.
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